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Measurements of mechanical asynchrony in patients with heart failure: is the puzzle completed?
- Publication Year :
- 2007
-
Abstract
- Numerous randomized clinical trials demonstrated the beneficial effects of cardiac resynchronization therapy (CRT) in the treatment of moderate to severe heart failure. Despite careful patient selection, there is still a percentage of non-responders, that is as high as 30-50%. Patients are selected mainly on electrocardiogram criteria. Recent studies have observed that the severity of mechanical systolic asynchrony is a much better predictor of a response after CRT. Echocardiography allows a non-invasive evaluation atrioventricular and inter- and intraventricular synchrony; furthermore, recent advances have provided direct evidence of wall motion resynchronization in patients receiving CRT. Nevertheless, although many authors tried to search for the best echocardiographic index to identify systolic asynchrony, and consequently responders to CRT before the procedure, this issue is still a matter of debate. Our aim was to make an updated review of the more recent studies on this topic.
- Subjects :
- Moderate to severe
medicine.medical_specialty
medicine.medical_treatment
Cardiac resynchronization therapy
law.invention
Randomized controlled trial
Heart Conduction System
law
Internal medicine
medicine
Humans
In patient
cardiovascular diseases
Wall motion
Beneficial effects
Heart Failure
business.industry
Cardiac Pacing, Artificial
Arrhythmias, Cardiac
General Medicine
medicine.disease
Myocardial Contraction
Asynchrony (computer programming)
Echocardiography
Heart failure
cardiovascular system
Cardiology
Cardiomyopathies
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....3edcbcba9855cf7eccb53c1a43596717