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Capsular Types of Vibrio vulnificus: An Analysis of Strains from Clinical and Environmental Sources
- Source :
- Journal of Infectious Diseases. 168:758-762
- Publication Year :
- 1993
- Publisher :
- Oxford University Press (OUP), 1993.
-
Abstract
- Vibrio vulnificus produces a capsular polysaccharide (CPS) that is essential for virulence. CPS from V. vulnificus clinical strain MO6-24 has been purified and the structure determined. In preliminary screening with antisera raised to MO6-24 CPS, 4 (19%) of 21 clinical isolates (including MO6-24), but none of 67 environmental V. vulnificus isolates, agglutinated with anti-MO6-24 antisera (P = .003). CPS was isolated from a subset of 12 clinical and 7 environmental isolates and analyzed by high-performance anion-exchange chromatography and one-dimensional nuclear magnetic resonance. MO6-24 and 1 other serologically positive strain had identical CPS structures; the other 2 serologically positive strains had substitutions in two of four sugar residues. Thirteen other capsular types were identified among the remaining 15 strains from which CPS was extracted.
- Subjects :
- Antiserum
Magnetic Resonance Spectroscopy
Strain (chemistry)
Polysaccharides, Bacterial
Virulence
Enzyme-Linked Immunosorbent Assay
Vibrio vulnificus
Cross Reactions
Biology
biology.organism_classification
Immune sera
Microbiology
Infectious Diseases
Vibrionaceae
Agglutination Tests
Vibrio Infections
Humans
Immunology and Allergy
Typing
Water Microbiology
Bacterial Capsules
Bacteria
Vibrio
Subjects
Details
- ISSN :
- 15376613 and 00221899
- Volume :
- 168
- Database :
- OpenAIRE
- Journal :
- Journal of Infectious Diseases
- Accession number :
- edsair.doi.dedup.....3e02411cab020d8a8c954003412f5d31