The heme-copper oxidase family consists of three distinct types of terminal oxidases and is related to nitric oxide reductase

Authors :: J.-W. L. De Gier
Walter G. Zumft
J. van der Oost
R. J. M. Van Spanning
A. H. Stouthamer
A. P. N. De Boer
Source :: van der Oost, J, de Boer, A P, de Gier, J-W, Zumft, W G, Stouthamer, A H & van Spanning, R J 1994, ' The heme-copper oxidase family consists of three distinct types of terminal oxidases and is related to nitric oxide reductase ', FEMS Microbiology Letters, vol. 121, no. 1, pp. 1-9 .
Publication Year :: 1994
Abstract: Among aerobic prokaryotes, many different terminal oxidase complexes have been described. Sequence comparison has revealed that the aa3-type cytochrome c oxidase and the bo3-type quinol oxidase are variations on the same theme: the heme-copper oxidase. A third member of this family has recently been recognized: the cbb3-type cytochrome c oxidase. Here we give an overview, and report that nitric oxide (NO) reductase, a bc-type cytochrome involved in denitrification, shares important features with these terminal oxidases as well. Tentative structural, functional and evolutionary implications are discussed.

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