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Effect ofPhyllanthus amarus on duck hepatitis B virus replication in vivo
- Source :
- Journal of Medical Virology. 32:212-218
- Publication Year :
- 1990
- Publisher :
- Wiley, 1990.
-
Abstract
- Nine ducks congenitally infected with the duck hepatitis B virus (DHBV) were treated either orally (four ducks for 10 weeks) or intraperitoneally (five ducks for 12 weeks) with the Indian traditional herbal remedy Phyllanthus amarus. Compared to placebo-treated control ducks, these treatments did not result in a reduction of circulating viral DNA in the serum or in the level of viral DNA replication in the liver. In two of the five intraperitoneal-treated ducks, a reduction in the levels of duck hepatitis B surface antigenaemia (DHBsAg) was observed. The data strongly suggest that Phyllanthus amarus has no significant inhibitory effect on DHBV DNA replication and only a minor effect on DHBsAg production.
- Subjects :
- animal structures
animal diseases
viruses
Duck hepatitis B virus
Virus Replication
medicine.disease_cause
Duck hepatitis virus
Virus
Hepatitis B Virus, Duck
Virology
medicine
Animals
Hepatitis B virus
Hepatitis B Surface Antigens
Plants, Medicinal
biology
virus diseases
Hepatitis B
biology.organism_classification
medicine.disease
Ducks
Infectious Diseases
Liver
Viral replication
Hepadnaviridae
DNA, Viral
Viral hepatitis
Subjects
Details
- ISSN :
- 10969071 and 01466615
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Journal of Medical Virology
- Accession number :
- edsair.doi.dedup.....3dcd29f009c83d6fa6401180c8b3cf5e