Effects of 12 weeks of beta-hydroxy-beta-methylbutyrate free acid, adenosine triphosphate, or a combination on muscle mass, strength, and power in resistance trained individuals

Adenosine-Triphosphate (ATP) supplementation maintains performance and increases volume under high fatiguing contractions. However, greater fatigue increases recovery demands between training sessions. Studies utilizing HMB free acid (HMB-FA) supplementation suggest that the supplement speeds regenerative capacity. However, we are unaware of studies investigating whether synergism exists between the two. Therefore, we investigated the effects of 12 weeks of HMB-FA, ATP, or a combination of the two on lean mass (LBM), strength, and power in trained individuals. We also determined these supplements effects on performance during an overreaching cycle.