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Composition of glycoproteins secreted by tracheal explants from various animal species

Authors :
Tokio Kaizu
Sheila A. Lyons
Carroll E. Cross
Mark D. Jennings
Jerold A. Last
Source :
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry. 62:195-200
Publication Year :
1979
Publisher :
Elsevier BV, 1979.

Abstract

1. 1. The acidic and neutral glycoproteins secreted by cultured tracheal explants from pigs, sheep, rats, mice, monkeys, guinea pigs, dogs and chickens were purified and fractionated by column chromatography on DEAE-cellulose and by electrophoresis on cellulose acetate. 2. 2. The ratios of acidic to neutral mucus glycoproteins were compared for the above animais with that of mucus glycoproteins secreted by cultured human bronchi. 3. 3. The observed ratios of acidic to neutral glycoproteins ranged from 4.0 (mouse) to 7.2 (chicken and pig) from cultured tracheae; secreted human bronchial mucus had a ratio of 2.7. 4. 4. The ratio of acidic to neutral glycoproteins secreted by tracheal explants varied with duration of incubation of the trachea in culture.

Details

ISSN :
03050491
Volume :
62
Database :
OpenAIRE
Journal :
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry
Accession number :
edsair.doi.dedup.....3d729d4d260ffc470d7891e2cc362cdd
Full Text :
https://doi.org/10.1016/0305-0491(79)90199-8