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PLANT NATRIURETIC PEPTIDE A and Its Putative Receptor PNP-R2 Antagonize Salicylic Acid–Mediated Signaling and Cell Death
- Source :
- Plant Cell
- Publication Year :
- 2020
- Publisher :
- Oxford University Press (OUP), 2020.
-
Abstract
- The plant stress hormone salicylic acid (SA) participates in local and systemic acquired resistance, which eventually leads to whole-plant resistance to bacterial pathogens. However, if SA-mediated signaling is not appropriately controlled, plants incur defense-associated fitness costs such as growth inhibition and cell death. Despite its importance, to date only a few components counteracting the SA-primed stress responses have been identified in Arabidopsis (Arabidopsis thaliana). These include other plant hormones such as jasmonic acid and abscisic acid, and proteins such as LESION SIMULATING DISEASE1, a transcription coregulator. Here, we describe PLANT NATRIURETIC PEPTIDE A (PNP-A), a functional analog to vertebrate atrial natriuretic peptides, that appears to antagonize the SA-mediated plant stress responses. While loss of PNP-A potentiates SA-mediated signaling, exogenous application of synthetic PNP-A or overexpression of PNP-A significantly compromises the SA-primed immune responses. Moreover, we identify a plasma membrane–localized receptor-like protein, PNP-R2, that interacts with PNP-A and is required to initiate the PNP-A–mediated intracellular signaling. In summary, our work identifies a peptide and its putative cognate receptor as counteracting both SA-mediated signaling and SA-primed cell death in Arabidopsis.
- Subjects :
- 0106 biological sciences
0301 basic medicine
Programmed cell death
medicine.drug_class
Arabidopsis
Plant Science
Biology
01 natural sciences
03 medical and health sciences
chemistry.chemical_compound
Gene Expression Regulation, Plant
Stress, Physiological
Plant Cells
Natriuretic peptide
medicine
Arabidopsis thaliana
heterocyclic compounds
Receptor
Research Articles
Cell Death
Arabidopsis Proteins
Jasmonic acid
Cell Membrane
Cell Biology
Plants, Genetically Modified
biology.organism_classification
Cell biology
DNA-Binding Proteins
030104 developmental biology
chemistry
Salicylic Acid
Systemic acquired resistance
Transcription Factors
010606 plant biology & botany
Hormone
Subjects
Details
- ISSN :
- 1532298X and 10404651
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- The Plant Cell
- Accession number :
- edsair.doi.dedup.....3d57a29d39569894de2e7b822775371b