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Molecular specializations of deep cortical layer analogs in songbirds
- Source :
- Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020), Scientific Reports
- Publication Year :
- 2020
- Publisher :
- Nature Publishing Group, 2020.
-
Abstract
- How the evolution of complex behavioral traits is associated with the emergence of novel brain pathways is largely unknown. Songbirds, like humans, learn vocalizations via tutor imitation and possess a specialized brain circuitry to support this behavior. In a comprehensive in situ hybridization effort, we show that the zebra finch vocal robust nucleus of the arcopallium (RA) shares numerous markers (e.g. SNCA, PVALB) with the adjacent dorsal intermediate arcopallium (AId), an avian analog of mammalian deep cortical layers with involvement in motor function. We also identify markers truly unique to RA and thus likely linked to modulation of vocal motor function (e.g. KCNC1, GABRE), including a subset of the known shared markers between RA and human laryngeal motor cortex (e.g. SLIT1, RTN4R, LINGO1, PLXNC1). The data provide novel insights into molecular features unique to vocal learning circuits, and lend support for the motor theory for vocal learning origin.
- Subjects :
- Male
0301 basic medicine
Arcopallium
media_common.quotation_subject
lcsh:Medicine
In situ hybridization
Biology
Molecular neuroscience
Article
03 medical and health sciences
Sensorimotor processing
0302 clinical medicine
Motor control
medicine
Animals
lcsh:Science
Zebra finch
In Situ Hybridization
LINGO1
media_common
Motor theory of speech perception
Multidisciplinary
Behavior, Animal
Gene Expression Profiling
lcsh:R
Motor Cortex
030104 developmental biology
medicine.anatomical_structure
Female
Vocal learning
lcsh:Q
Finches
Vocalization, Animal
Imitation
Neuroscience
030217 neurology & neurosurgery
Motor cortex
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....3d1b434d7a0f42c6f194000e225f6910
- Full Text :
- https://doi.org/10.1038/s41598-020-75773-4