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Supplementary Figures 1-3 and Table1 from Nanobody Targeting of Epidermal Growth Factor Receptor (EGFR) Ectodomain Variants Overcomes Resistance to Therapeutic EGFR Antibodies

Authors :
Mascha Binder
Friedrich Koch-Nolte
Matthias Peipp
Thomas Valerius
Thies Rösner
Carsten Bokemeyer
Kerstin Schuetze
Kristoffer Riecken
Boris Fehse
Peter Bannas
William Fumey
Johannes Finter
Marie Trentmann
Friederike Braig
Christoph Schultheiß
Natalie Baum
Joseph Tintelnot
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Figure 1 shows Nanobody 7D12 block of different EGFR ligands; Supplementary Figure 2 shows EGFR expression and EGF stimulated growth of mutated EGFR variants; Supplementary Figure 3 shows phage display experiments; Supplementary Table 1 shows EGFR primers.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....3d10bbc89bc02ce5736c126786618109
Full Text :
https://doi.org/10.1158/1535-7163.22505809