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The role of dopamine in mood disorders
- Source :
- Comprehensive Psychiatry, Vol 33, Iss 2, Pp 115-120 (1992)
- Publication Year :
- 1992
- Publisher :
- Elsevier, 1992.
-
Abstract
- The findings on dopamine in mood disorders suggest that decreased dopamine activity is involved in depression, while increased dopamine function contributes to mania. This report reviews the considerable preclinical and clinical evidence supporting this hypothesis, with particular emphasis on specific subtypes of depression. We also discuss the importance of integrating these dopamine findings with dopamine brain circuitry and with other neurotransmitter theories of affective disorders.
- Subjects :
- Male
Imipramine
Bipolar Disorder
lcsh:RC435-571
Dopamine
Neurotransmission
chemistry.chemical_compound
Piribedil
lcsh:Psychiatry
medicine
Humans
Neurotransmitter
Decreased Dopamine Activity
Bromocriptine
Depression (differential diagnoses)
Brain Chemistry
Depressive Disorder
Neurotransmitter Agents
medicine.disease
Psychiatry and Mental health
Clinical Psychology
chemistry
Mood disorders
Female
medicine.symptom
Psychology
Mania
Neuroscience
medicine.drug
Brain circuitry
Subjects
Details
- Language :
- English
- Volume :
- 33
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Comprehensive Psychiatry
- Accession number :
- edsair.doi.dedup.....3d0695d994212cd73cf1afc934bf62d7