Fig. S6 from Metastatic Conditioning of Myeloid Cells at a Subcutaneous Synthetic Niche Reflects Disease Progression and Predicts Therapeutic Outcomes

Statistical plots to support heatmaps in main text and supplementary materials. (a) Box plots for gene panel heatmap in Fig. 1f show the median, 25th-75th percentiles and most extreme data points that were not considered outliers (outliers are visually indicated by red +). TB cohort expression is centered relative to the time-matched TFC cohort median. Scale depicts the log2-transformed fold change. A two-way MANOVA showed a significant interaction effect between condition and time (Pillai's Trace=1.276, F(20,28)=2.465, p=0.014). Post hoc univariate ANOVA showed significant differences within the diseased cohort over time (indicated by #, df=(2,22), p