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Correlation between Gut Microbiota and Six Facets of Neuroticism in Korean Adults
- Source :
- Journal of Personalized Medicine; Volume 11; Issue 12; Pages: 1246, Journal of Personalized Medicine, Journal of Personalized Medicine, Vol 11, Iss 1246, p 1246 (2021)
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2021.
-
Abstract
- A person high in neuroticism is more likely to experience anxiety, stress, worry, fear, anger, and depression. Previous studies have shown that the gut microbiota can influence personality and mental disorders, including stress, anxiety, and depression, through the gut–brain axis. Here, we investigated the correlations between the sub-facet of neuroticism and gut microbiota using the Revised NEO Personality Inventory and the 16S rRNA gene sequencing data 784 adults. We found that the high anxiety and vulnerability group showed significantly lower richness in microbial diversity than a group with low anxiety and vulnerability. In beta diversity, there was a significant difference between the low and high groups of anxiety, self-consciousness, impulsiveness, and vulnerability. In taxonomic compositions, Haemophilus belonging to Gammaproteobacteria was correlated with the Neuroticism domain as well as N1 anxiety and N6 vulnerability facets. The high N1 anxiety and N6 vulnerability group was correlated with a low abundance of Christensenellaceae belonging to Firmicutes Clostridia. High N4 self-consciousness was correlated with a low abundance of Alistipes and Sudoligranulum. N5 impulsiveness was correlated with a low abundance of Oscillospirales. Our findings will contribute to uncovering the potential link between the gut microbiota and neuroticism, and the elucidation of the correlations of the microbiome–gut–brain axis with behavioral changes and psychiatric cases in the general population.
- Subjects :
- media_common.quotation_subject
Population
Gut–brain axis
vulnerability
16s sequencing
Medicine (miscellaneous)
Gut flora
Article
Revised NEO Personality Inventory
medicine
microbiota
Personality
neuroticism
education
gut–brain axis
anxiety
depression
media_common
education.field_of_study
biology
biology.organism_classification
Neuroticism
Medicine
Anxiety
medicine.symptom
Worry
Clinical psychology
Subjects
Details
- Language :
- English
- ISSN :
- 20754426
- Database :
- OpenAIRE
- Journal :
- Journal of Personalized Medicine; Volume 11; Issue 12; Pages: 1246
- Accession number :
- edsair.doi.dedup.....3bf65afcef7f3741cf9f5317ec9445e4
- Full Text :
- https://doi.org/10.3390/jpm11121246