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Incidence and risk factor for ventilator-associated pneumonia in Kathmandu University Hospital
- Source :
- Kathmandu University medical journal (KUMJ). 9(33)
- Publication Year :
- 2012
-
Abstract
- Background Ventilator associated pneumonia is a major cause of morbidity in the intensive care unit. Difficulties in identification of the risk factors, in diagnosing and in prevention, have intensified the problem. Objectives To measure the incidence of ventilator associated pneumonia in intensive care unit and to identify the risk factors associated. Methods A prospective observational cohort study of 69 patients who were mechanically ventilated for more than 48 hours were evaluated to find out the development of nosocomial pneumonia and presence or absence of risk factors. Data were subjected to univariate analysis using chi-square and t-test. Level of significance was set at 0.05. Results Twenty two (31.88%) out of 69 patients developed ventilator associated pneumonia, majority of them between four days to 14 days. Reintubation, invasive lines, H 2 blockers and low PaO 2 /FiO 2 were identified as major risk factors in our study. Enteral feeding via nasogastric tube and use of steroids was not associated with development of ventilator associated pneumonia. The patients with ventilator associated pneumonia had significantly longer duration of mechanical ventilation (18.88±7.7 days vs 7.36±4.19 days) and stay (29±17.8 days vs 9.22±5.14 days). The morality was similar for both the groups with or without ventilator associated pneumonia. Conclusion The incidence of ventilator pneumonia is high. Patients requiring prolonged ventilation, re-intubation, more invasive lines and H 2 blockers, are at high risk and need special attention towards prevention. http://dx.doi.org/10.3126/kumj.v9i1.6258 Kathmandu Univ Med J 2011;9(1):28-31
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
Adolescent
medicine.medical_treatment
law.invention
Hospitals, University
Young Adult
Nepal
law
Risk Factors
medicine
Humans
Prospective Studies
Risk factor
Intensive care medicine
Prospective cohort study
Aged
Mechanical ventilation
business.industry
Incidence (epidemiology)
Incidence
Ventilator-associated pneumonia
Pneumonia, Ventilator-Associated
General Medicine
Middle Aged
medicine.disease
Intensive care unit
Pneumonia
Intensive Care Units
Emergency medicine
Female
business
Cohort study
Subjects
Details
- ISSN :
- 18122078
- Volume :
- 9
- Issue :
- 33
- Database :
- OpenAIRE
- Journal :
- Kathmandu University medical journal (KUMJ)
- Accession number :
- edsair.doi.dedup.....3bcce0dc9977ebacc50a467254aa6f16