Back to Search
Start Over
Erratum to: Population attributable risks of modifiable reproductive factors for breast and ovarian cancers in Korea
- Source :
- BMC Cancer
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Breast and ovarian cancers are predominant female cancers with increasing prevalence. The purpose of this study was to estimate the population attributable risks (PARs) of breast and ovarian cancer occurrence based on the relative risks (RRs) of modifiable reproductive factors and population-specific exposure prevalence.The PAR was calculated by using the 1990 standardized prevalence rates, the 2010 national cancer incidence with a 20 year lag period, the meta-analyzed RRs from studies conducted in the Korean population for breast cancer, and the meta-analyzed RRs from a Korean epithelial ovarian cancer study and a prior meta-analysis, and ovarian cancer cohort results up to 2012. For oral contraceptive and hormone replacement therapy use, we did not consider lag period.The summary PARs for modifiable reproductive factors were 16.7% (95% CI 15.8-17.6) for breast cancer (2404 cases) and 81.9% (95% CI 55.0-100.0) for ovarian cancer (1579 cases). The modifiable reproductive factors included pregnancy/age at first birth (8.0%), total period of breastfeeding (3.1%), oral contraceptive use (5.3%), and hormone replacement therapy use (0.3%) for breast cancer and included breastfeeding experience (2.9%), pregnancy (1.2%), tubal ligation (24.5%), and oral contraceptive use (53.3%) for ovarian cancer.Despite inherent uncertainties in the risk factors for breast and ovarian cancers, we suggest that appropriate long-term control of modifiable reproductive factors could reduce breast and ovarian cancer incidences and their related burdens by 16.7% and 81.9%, respectively.
- Subjects :
- Adult
0301 basic medicine
Oncology
Cancer Research
medicine.medical_specialty
Population
Breast Neoplasms
03 medical and health sciences
0302 clinical medicine
Pregnancy
Risk Factors
Internal medicine
Republic of Korea
Genetics
medicine
Humans
education
Reproductive History
Ovarian Neoplasms
education.field_of_study
business.industry
Reproduction
Cancer
Reproductive Factors
medicine.disease
030104 developmental biology
030220 oncology & carcinogenesis
Female
Erratum
business
Contraceptives, Oral
Maternal Age
Subjects
Details
- ISSN :
- 14712407
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- BMC Cancer
- Accession number :
- edsair.doi.dedup.....3b7118ece88caba939dd14f5c81d616b
- Full Text :
- https://doi.org/10.1186/s12885-016-2216-2