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Using the Patient-Reported Outcomes Measurement Information System (PROMIS) to measure symptom burden reported by patients with brain tumors
- Source :
- Pediatric bloodcancer. 66(3)
- Publication Year :
- 2018
-
Abstract
- BACKGROUND: Children with brain tumors can experience symptom burden throughout their disease continuum. The aim of the study was to evaluate symptom burden reported by children with brain tumors and factors that potentially were associated with their symptoms. METHODS: Data from 199 children with brain tumors aged 7–22 (mean age=14 years; 52% males; 76% white) were analyzed. Symptom burden was assessed using Patient Reported Outcomes Measurement Information System (PROMIS) via computerized adaptive testing (CAT) – Anxiety, Depression, Fatigue, Mobility, Upper Extremity Function, Peer Relationship, and Cognition. Patients and parents completed Symptom Distress Scales (SDS). Test-statistics and ANOVA were used to evaluate relationships between PROMIS measures and potentially influential variables. RESULTS: Significant results (p1 yr). Fatigue and Cognition were associated with educational program (regular classroom without an individualized education plan versus those that had an individualized education plan); Mobility and Upper Extremity Function were associated with time since last radiation. Mobility, Upper Extremity Function and Anxiety were associated with time since last chemotherapy. CONCLUSIONS: Significant associations were found between PROMIS and SDS as well as clinical and demographic characteristics. Brief-yet-precise PROMIS CATs can be used to systematically assess symptom burden experienced by children with brain tumors.
- Subjects :
- Adult
Male
Patient-Reported Outcomes Measurement Information System
medicine.medical_specialty
Adolescent
Brain tumor
Disease
Article
Upper Extremity
03 medical and health sciences
Young Adult
0302 clinical medicine
medicine
Humans
Patient Reported Outcome Measures
Child
Depression (differential diagnoses)
Fatigue
Pain Measurement
business.industry
Brain Neoplasms
Depression
Patient-centered outcomes
Cognition
Hematology
medicine.disease
Prognosis
Anxiety Disorders
Combined Modality Therapy
Oncology
030220 oncology & carcinogenesis
Pediatrics, Perinatology and Child Health
Physical therapy
Quality of Life
Anxiety
Female
Computerized adaptive testing
medicine.symptom
business
030215 immunology
Follow-Up Studies
Information Systems
Subjects
Details
- ISSN :
- 15455017
- Volume :
- 66
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Pediatric bloodcancer
- Accession number :
- edsair.doi.dedup.....3b2f0c416f1af5f7abd63000e4a41c1d