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3D digital breast cancer models with multimodal fusion algorithms
- Source :
- The Breast : official journal of the European Society of Mastology, Breast, Vol 49, Iss, Pp 281-290 (2020)
- Publication Year :
- 2020
- Publisher :
- Elsevier, 2020.
-
Abstract
- Breast cancer image fusion consists of registering and visualizing different sets of a patient synchronized torso and radiological images into a 3D model. Breast spatial interpretation and visualization by the treating physician can be augmented with a patient-specific digital breast model that integrates radiological images. But the absence of a ground truth for a good correlation between surface and radiological information has impaired the development of potential clinical applications. A new image acquisition protocol was designed to acquire breast Magnetic Resonance Imaging (MRI) and 3D surface scan data with surface markers on the patient’s breasts and torso. A patient-specific digital breast model integrating the real breast torso and the tumor location was created and validated with a MRI/3D surface scan fusion algorithm in 16 breast cancer patients. This protocol was used to quantify breast shape differences between different modalities, and to measure the target registration error of several variants of the MRI/3D scan fusion algorithm. The fusion of single breasts without the biomechanical model of pose transformation had acceptable registration errors and accurate tumor locations. The performance of the fusion algorithm was not affected by breast volume. Further research and virtual clinical interfaces could lead to fast integration of this fusion technology into clinical practice.<br />Highlights • MRI/3D surface scan fusion algorithm to create 3D breast cancer models. • A replicable clinical validation protocol for MRI/3D surface scan fusion algorithms. • Anthropometric study that quantifies breast deformations by area in MRI and 3D scans.
- Subjects :
- Adult
Models, Anatomic
Multimodal fusion
3D breast model
Breast Neoplasms
Breast magnetic resonance imaging
lcsh:RC254-282
Multimodal Imaging
03 medical and health sciences
Magnetic resonance imaging
0302 clinical medicine
Breast cancer
Imaging, Three-Dimensional
SDG 3 - Good Health and Well-being
medicine
Humans
Computer Simulation
030212 general & internal medicine
Breast
skin and connective tissue diseases
Fusion
Ground truth
Image fusion
medicine.diagnostic_test
business.industry
General Medicine
Torso
Virtual special issue: Artificial Intelligence in Breast Cancer Care
Edited by Nehmat Houssami, Maria João Cardoso, Giuseppe Pozzi and Brigitte Seroussi
Middle Aged
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
medicine.disease
Magnetic Resonance Imaging
Visualization
Surface
medicine.anatomical_structure
030220 oncology & carcinogenesis
Surgery
Multimodal registration
Female
business
Algorithm
Algorithms
Subjects
Details
- Language :
- English
- ISSN :
- 15323080 and 09609776
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- The Breast : official journal of the European Society of Mastology
- Accession number :
- edsair.doi.dedup.....3b0f6608c517a2d31e4fd50fe0c4ec16