Additional file 1 of Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15

Additional file 1: Table S1. Related to Figure S2. List of gene symbols, adjusted p-values, and log2 fold changes after 16-hr treatment with BAM15. Figure S1. Related to Figure 1. BAM15-mediated mitochondrial uncoupling reduces cell viability, proliferation, and migration in human TNBC and murine luminal B breast cancer cells. Figure S2. Related to Figure 2. BAM15 reduces the expression of genes required for cellular proliferation and energy production in MDA-MB-231 cells. Figure S3. Related to Figure 3. BAM15 reduces OXPHOS and glycolytic capacity via ΔΨm destabilization in MDA-MB-231 and EO771 cells. Figure S4. Related to Figure 4. BAM15 suppresses tumor growth in C57BL/6J mice.