Back to Search
Start Over
Value of ultrafast and standard dynamic contrast-enhanced magnetic resonance imaging in the evaluation of the presence and extension of residual disease after neoadjuvant chemotherapy in breast cancer
- Source :
- Japanese Journal of Radiology. 39:791-801
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- To evaluate the diagnostic performance of ultrafast and standard dynamic contrast-enhanced (DCE)-MRI in evaluating the residual disease after neoadjuvant chemotherapy (NAC) for breast cancer. Sixty-seven consecutive patients underwent MRI after NAC. Visual analysis of enhancement was performed on ultrafast and standard DCE-MRI, and compared between no residual disease and residual disease groups. The lesion diameters measured on the last phase of ultrafast DCE-MRI and early and delayed phases of standard DCE-MRI were compared with pathological diameter of entire residual cancer and residual invasive ductal carcinoma (IDC). The visual analysis in the delayed phase of standard DCE-MRI exhibited the highest sensitivity (90%), whereas ultrafast DCE-MRI revealed the highest positive predictive value (92%). There were no significant differences between the diameters in the delayed phase of the standard DCE-MRI and the pathological entire residual cancer (p = 0.97), and the diameters in ultrafast DCE-MRI and the pathological residual IDC (p = 0.97). The delayed phase of standard DCE-MRI may be effective for detecting the residual disease and evaluating the extension of entire residual cancer. Enhancement in ultrafast DCE-MRI may be strongly suggestive of the presence of residual disease, and effective for evaluating the extension of residual IDC.
- Subjects :
- Neoplasm, Residual
Time Factors
medicine.medical_treatment
Contrast Media
Breast Neoplasms
Disease
Residual
030218 nuclear medicine & medical imaging
Lesion
03 medical and health sciences
0302 clinical medicine
Breast cancer
medicine
Humans
Radiology, Nuclear Medicine and imaging
skin and connective tissue diseases
Chemotherapy
medicine.diagnostic_test
business.industry
Magnetic resonance imaging
medicine.disease
Magnetic Resonance Imaging
Neoadjuvant Therapy
Radiation therapy
Dynamic contrast
030220 oncology & carcinogenesis
Female
medicine.symptom
business
Nuclear medicine
Subjects
Details
- ISSN :
- 1867108X and 18671071
- Volume :
- 39
- Database :
- OpenAIRE
- Journal :
- Japanese Journal of Radiology
- Accession number :
- edsair.doi.dedup.....3ae35314b25acab26a6b2b76d5715c7f