A rationally designed macrocyclic cavitand that kills bacteria with high efficacy and good selectivity

Authors :: Sangyong Jon
Jinny Choi
Jae Il Kim
Jeeyeon Kim
Sung-Tae Yang
Kimoon Kim
Source :: Chemical Communications. :1151
Publication Year :: 2007
Publisher :: Royal Society of Chemistry (RSC), 2007.
Abstract: An amphiphilic macrocyclic cavitand that shows good antibacterial activity, comparable to that of peptide-based antibiotics was developed by rational design and its antibacterial selectivity over mammalian cells was examined.

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