Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen

Authors :: Victor Clausse
Yuhong Fang
Dingyin Tao
Harichandra D. Tagad
Hongmao Sun
Yuhong Wang
Surendra Karavadhi
Kelly Lane
Zhen-Dan Shi
Olga Vasalatiy
Christopher A. LeClair
Rebecca Eells
Min Shen
Samarjit Patnaik
Ettore Appella
Nathan P. Coussens
Matthew D. Hall
Daniel H. Appella
Source :: ACS Pharmacology & Translational Science. 5:993-1006
Publication Year :: 2022
Publisher :: American Chemical Society (ACS), 2022.
Abstract: Wild-type P53-induced phosphatase 1 (WIP1), also known as

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