Figures S1-S7, Tables S1-S10 from PBX3 Is Part of an EMT Regulatory Network and Indicates Poor Outcome in Colorectal Cancer

Figure S1. Specificity of PBX3 protein detection. Figure S2. Effects of WNT repression on PBX3 in colon cancer cells. Figure S3. Lack of transcriptional regulation of PBX3 expression by WNT. Figure S4. Effects of EMT induction with a conditional ZEB1 allele in LS174T and DLD-1 colon cancer cells. Figure S5. Effects of ZEB1 depletion on PBX3 expression. Figure S6. Effects of PBX3 depletion on VIM expression upon EMT induction by SNAIL. Figure S7. PBX3, ZEB1 and SNAIL mRNA expression and disease free survival in n=786 colon cancer cases. Table S1. Antibodies used. Table S2. qRT-PCR primers. Table S3. Differentially expressed transcription factors. Table S4. PBX3 in UICC II colorectal cancer. Table S5. Multivariate analysis of cancer specific survival in UICC stage II colorectal cancer. Table S6. Multivariate analysis of disease free survival in UICC stage II colorectal cancer. Table S7. PBX3 expression in colon cancers with and without distant metastasis. Table S8. Multivariate analysis for PBX3 mRNA expression. Table S9. Multivariate analysis for ZEB1 mRNA expression. Table S10. Multivariate analysis for SNAIL mRNA expression.