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Within-patient comparison of His-bundle pacing, right ventricular pacing, and right ventricular pacing avoidance algorithms in patients with PR prolongation: Acute hemodynamic study
- Source :
- Journal of cardiovascular electrophysiologyREFERENCES. 31(11)
- Publication Year :
- 2020
-
Abstract
- Aims A prolonged PR interval may adversely affect ventricular filling and, therefore, cardiac function. AV delay can be corrected using right ventricular pacing (RVP), but this induces ventricular dyssynchrony, itself harmful. Therefore, in intermittent heart block, pacing avoidance algorithms are often implemented. We tested His‐bundle pacing (HBP) as an alternative. Methods Outpatients with a long PR interval (>200 ms) and intermittent need for ventricular pacing were recruited. We measured within‐patient differences in high‐precision hemodynamics between AV‐optimized RVP and HBP, as well as a pacing avoidance algorithm (Managed Ventricular Pacing [MVP]). Results We recruited 18 patients. Mean left ventricular ejection fraction was 44.3 ± 9%. Mean intrinsic PR interval was 266 ± 42 ms and QRS duration was 123 ± 29 ms. RVP lengthened QRS duration (+54 ms, 95% CI 42–67 ms, p
- Subjects :
- Bradycardia
Bundle of His
Cardiac & Cardiovascular Systems
CARDIAC-RESYNCHRONIZATION
Heart block
pacing avoidance algorithms
Hemodynamics
IMPROVEMENT
030204 cardiovascular system & hematology
AV optimization
Ventricular Function, Left
03 medical and health sciences
QRS complex
0302 clinical medicine
Physiology (medical)
INTERVAL
Medicine
Humans
030212 general & internal medicine
PR interval
Ventricular dyssynchrony
1102 Cardiorespiratory Medicine and Haematology
OUTCOMES
Science & Technology
Ejection fraction
business.industry
DUAL-CHAMBER
MORTALITY
Cardiac Pacing, Artificial
Stroke Volume
His-bundle pacing
medicine.disease
DYSFUNCTION
Treatment Outcome
Cardiovascular System & Hematology
Heart failure
Cardiovascular System & Cardiology
BLOCK
cardiovascular system
prolonged PR interval
HEART-FAILURE
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Life Sciences & Biomedicine
Algorithm
Algorithms
Subjects
Details
- ISSN :
- 15408167
- Volume :
- 31
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Journal of cardiovascular electrophysiologyREFERENCES
- Accession number :
- edsair.doi.dedup.....3a67b75d805ac5388359d4511cc553d5