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High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia

Authors :
Alessandro Coppe
Andrea Binatti
Noriko Senoo
Thomas P. Loughran
Hitoshi Sakai
Hideyuki Nakazawa
Nodoka Sekiguchi
Pekka Ellonen
Noriyasu Fukushima
Sonja Lagström
Satu Mustjoki
Fumihiro Ishida
Sayaka Nishina
Takeki Mitsui
Emma I. Andersson
Sabrina Bortoluzzi
Samuli Eldfors
Stefania Bortoluzzi
Yok-Lam Kwong
Kazuyuki Matsuda
Toru Kawakami
Jaroslaw P. Maciejewski
Takahiro Tanahashi
Vanessa Rebecca Gasparini
Source :
Blood
Publication Year :
2016

Abstract

To the editor: Large granular lymphocyte (LGL) leukemia is a group of chronic lymphoproliferative disorders of cytotoxic T or natural killer (NK) cells frequently complicated with cytopenia and autoimmune phenomena.[1][1],[2][2] In the current World Health Organization (WHO) classification, T-LGL

Details

ISSN :
00064971
Database :
OpenAIRE
Journal :
Blood
Accession number :
edsair.doi.dedup.....3a6203aa9e4cbf4d01d2a17eae1bbe56
Full Text :
https://doi.org/10.1182/blood-2016-06-724856