Back to Search
Start Over
High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia
- Source :
- Blood
- Publication Year :
- 2016
-
Abstract
- To the editor: Large granular lymphocyte (LGL) leukemia is a group of chronic lymphoproliferative disorders of cytotoxic T or natural killer (NK) cells frequently complicated with cytopenia and autoimmune phenomena.[1][1],[2][2] In the current World Health Organization (WHO) classification, T-LGL
- Subjects :
- CD4-Positive T-Lymphocytes
Male
0301 basic medicine
Lymphocyte
Immunology
Lymphoproliferative disorders
Letters to Blood
chemical and pharmacologic phenomena
Biology
medicine.disease_cause
Biochemistry
Pathogenesis
03 medical and health sciences
0302 clinical medicine
hemic and lymphatic diseases
STAT5 Transcription Factor
medicine
Humans
Cytotoxic T cell
T-Cell Large Granular Lymphocyte Leukemia
Aged
Aged, 80 and over
Cytopenia
Mutation
Incidence
Cell Biology
Hematology
Middle Aged
medicine.disease
Neoplasm Proteins
3. Good health
Leukemia, Large Granular Lymphocytic
Leukemia
030104 developmental biology
medicine.anatomical_structure
030220 oncology & carcinogenesis
Female
Subjects
Details
- ISSN :
- 00064971
- Database :
- OpenAIRE
- Journal :
- Blood
- Accession number :
- edsair.doi.dedup.....3a6203aa9e4cbf4d01d2a17eae1bbe56
- Full Text :
- https://doi.org/10.1182/blood-2016-06-724856