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Antibody Dynamics of 2009 Influenza A (H1N1) Virus in Infected Patients and Vaccinated People in China
- Source :
- PLoS ONE, PLoS ONE, Vol 6, Iss 2, p e16809 (2011)
- Publication Year :
- 2011
- Publisher :
- Public Library of Science (PLoS), 2011.
-
Abstract
- Background To evaluate the risk of the recurrence and the efficiency of the vaccination, we followed-up antibody responses in patients with the 2009 pandemic H1N1 influenza and persons who received the pandemic H1N1 vaccine in Guangzhou China. Methods We collected serum samples from 129 patients and 86 vaccinated persons at day 0, 15, 30, 180 after the disease onset or the vaccination, respectively. Antibody titers in these serum samples were determined by haemagglutination inhibition (HI) assay using a local isolated virus strain A/Guangdong Liwan/SWL1538/2009(H1N1). Results HI antibody positive rate of the patients increased significantly from 0% to 60% at day 15 (χ2 = 78, P
- Subjects :
- Male
Viral Diseases
Anatomy and Physiology
Epidemiology
lcsh:Medicine
Antibodies, Viral
medicine.disease_cause
Gastroenterology
Disease Outbreaks
Influenza A Virus, H1N1 Subtype
Recurrence
Immune Physiology
Influenza A virus
lcsh:Science
Immune Response
Multidisciplinary
biology
Viral Vaccine
Vaccination
Antibody titer
Middle Aged
Titer
Infectious Diseases
Influenza Vaccines
Medicine
Female
Antibody
Research Article
Adult
Risk
China
medicine.medical_specialty
Antibodies
Infectious Disease Epidemiology
Young Adult
Immunity
Internal medicine
Influenza, Human
medicine
Humans
Seroconversion
business.industry
lcsh:R
Influenza
Immunology
biology.protein
lcsh:Q
Clinical Immunology
business
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....3a45ef04a0f991877843368c3313f7a0