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Dextrose gel treatment does not impair subsequent feeding
- Source :
- Archives of disease in childhood. Fetal and neonatal edition. 102(6)
- Publication Year :
- 2017
-
Abstract
- Background Dextrose gel is increasingly used as first-line treatment for neonatal hypoglycaemia. Treatment with 400 mg/kg previously has been reported to impair subsequent feeding. We sought to determine if the recommended dose of 200 mg/kg altered feeding. Methods Hypoglycaemic babies were randomised to 200 mg/kg dextrose gel or placebo and fed. Prefeed alertness, quality and duration of breast feeding, and the volume of formula taken were assessed on the next feeding. Results Prefeed alertness scores were similar in babies (n=211) treated with dextrose or placebo gel (124 episodes, OR=1.30 (95% CI 0.62 to 2.77), p=0.49). Breastfed babies were more likely to have good feeding scores after dextrose gel (160 episodes, OR=3.54 (95% CI 1.30 to 9.67), p=0.01) but similar breastfeeding duration (57 episodes, median (range) 20 (3–90) vs 25 (2–80) min, p=0.62). Formula volumes taken were also similar (24 episodes, median (range) 4.6 (2.2–11.3) vs 6.4 (2.0–8.9) mL/kg, p=0.30). Conclusions Treating hypoglycaemic babies with dextrose gel 200 mg/kg does not depress subsequent feeding and may improve breastfeeding quality. Trial registration number ACTRN 12608000623392.
- Subjects :
- Blood Glucose
medicine.medical_specialty
Breastfeeding
Hypoglycemia
Placebo
03 medical and health sciences
0302 clinical medicine
Double-Blind Method
030225 pediatrics
medicine
Humans
030212 general & internal medicine
Neonatology
Trial registration
Infant feeding
business.industry
Infant, Newborn
Obstetrics and Gynecology
General Medicine
medicine.disease
Surgery
Breast Feeding
Glucose
Neonatal hypoglycaemia
Anesthesia
Pediatrics, Perinatology and Child Health
business
Breast feeding
Subjects
Details
- ISSN :
- 14682052
- Volume :
- 102
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Archives of disease in childhood. Fetal and neonatal edition
- Accession number :
- edsair.doi.dedup.....3a256ef3469e3c994a0181bffa7c2a60