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Retrospective analysis of the effects of Blastomyces antigen concentration in urine and radiographic findings on survival in dogs with blastomycosis
- Source :
- Journal of Veterinary Internal Medicine, Vol 35, Iss 2, Pp 946-953 (2021), Journal of Veterinary Internal Medicine
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background The Blastomyces antigen concentration in urine (BACU) test is used to diagnose blastomycosis and monitor treatment in dogs. It is unknown if a higher BACU is associated with shorter survival. Objectives To determine if the magnitude of BACU before treatment is associated with survival in dogs with blastomycosis. Animals Fifty‐two dogs with blastomycosis. Methods Retrospective case review. BACU, radiographic lung severity (RLS) score (0‐4 scale), and survival time up to 1 year after diagnosis were obtained through medical record review of dogs with Blastomyces dermatitidis. Results The overall survival was: discharge, 87%; 1 week, 85%; 2 months, 74%; and 6 months, 69%. BACU correlated with RLS score (r s = 0.33, P = .02). BACU and RLS scores were lower in survivors to 2 months than nonsurvivors (average BACU difference of 2.5 ng/mL, 95% confidence interval [CI]: 0.2‐4.8 ng/mL, P = .04; median RLS difference of 2; range, 0‐4, P = .02). Dogs with BACU 5 ng/mL (P = .03) and dogs with severe (3‐4) RLS scores (P = .04). All dogs with a BACU
- Subjects :
- medicine.medical_specialty
Antigens, Fungal
040301 veterinary sciences
Radiography
canine
Infectious Disease
Standard Article
Urine
030204 cardiovascular system & hematology
Gastroenterology
survival
Blastomycosis
0403 veterinary science
03 medical and health sciences
Dogs
0302 clinical medicine
Internal medicine
mental disorders
medicine
Animals
Dog Diseases
Antibodies, Fungal
Retrospective Studies
Blastomyces
Lung
lcsh:Veterinary medicine
General Veterinary
biology
Blastomyces dermatitidis
business.industry
Retrospective cohort study
04 agricultural and veterinary sciences
biology.organism_classification
medicine.disease
Standard Articles
Confidence interval
medicine.anatomical_structure
lcsh:SF600-1100
SMALL ANIMAL
prognosis
systemic fungal infection
business
Subjects
Details
- Language :
- English
- ISSN :
- 08916640 and 19391676
- Volume :
- 35
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Internal Medicine
- Accession number :
- edsair.doi.dedup.....3a222ffd07e1761552c208373d94251a