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Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6
- Publication Year :
- 2023
- Publisher :
- Zenodo, 2023.
-
Abstract
- These data are the R scripts, environments, output used for analyzing chemoproteomics data. The volcano plot shown in the manuscript is based on the DEP R package. To validate the enrichment output from DEP, the proteomics data was also processed with the proDA package. Filename (7 files) Description combined_protein_Int.txt Output from database search hdac6_dep_submitted.R script used to process data (from DEP package) hdac6_dep_submitted.R.RData workspace environment from DEP package hdac6probecontrol_dep.csv exported list of p-value and fold-change from DEP hdac6probecontrol_proda.csv exported list of p-value and fold-change from proDA hdac6proda_submitted.R proDA script hdac6proda_submitted.RData proDA workspace environment<br />PXD039880 - the raw data is also uploaded to PRIDE.
- Subjects :
- open source
ubiquitin binding domain
chemical tool
ubiquitin
chemical probe
UBD
HDAC6
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....3a1d88eee8c05d3f84ad9eac6e95b802
- Full Text :
- https://doi.org/10.5281/zenodo.7618094