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Open versus minimally invasive esophagectomy: clinical outcomes for locally advanced esophageal adenocarcinoma
- Source :
- Surgical endoscopy. 29(9)
- Publication Year :
- 2014
-
Abstract
- We compared oncologic and surgical outcome between minimally invasive esophagectomy (MIE) and the Ivor Lewis-type open approach (OE) in the treatment of locally advanced esophageal adenocarcinoma (EAC).Of 284 patients undergoing surgery for EAC between 2003 and 2013, the 153 selected with locally advanced EAC were 74 MIEs and 79 OEs [median age, 66 for MIE, 63 for OE (p = 0.009)]. Neoadjuvant therapy was given to 82% of MIEs and 78% of OEs. In the OE group, 86% was male, and in the MIE group, 78%. Data assessed were oncologic, intraoperative, and postoperative.Mortality at 30 days was 3% for MIE and 1% for OE; and 90-day mortality was 4% for MIE and 5% for OE. The complication rate for MIE was 50%, and 60% for OE (p = 0.181). The pneumonia rate was 18% for MIE and 19% for OE; leak rate was 7% for MIE and 6% for OE; conduit necrosis was 0 for MIE and 3% for OE; and rate of airway-conduit fistula was 3% for MIE and 1 % for OE. Median blood loss (MIE 300 vs. OE 800, p0.0001), overall stay (MIE 13 vs. OE 14, p = 0.040), and harvested lymph nodes (MIE 20 vs. OE 22, p = 0.021) all were in favor of MIE. Median ICU stay and operative time did not differ. Neither did overall (OS) nor recurrence-free (RFS) 3-year survival differs significantly (MIE 64% vs. OS OE 49%, MIE 57% vs. RFS OE 53%).In our institution, MIE appears to produce oncologic and survival results similar to those of OE. Shorter length of stay and less operative blood loss may reduce costs for MIE.
- Subjects :
- Adult
Male
medicine.medical_specialty
Esophageal Neoplasms
Locally advanced
Blood Loss, Surgical
Esophageal adenocarcinoma
Adenocarcinoma
Postoperative Complications
Blood loss
Invasive esophagectomy
Carcinoma
Medicine
Humans
Minimally Invasive Surgical Procedures
Finland
Aged
Retrospective Studies
Aged, 80 and over
business.industry
General surgery
Retrospective cohort study
Pneumonia
Length of Stay
Middle Aged
medicine.disease
Surgery
Esophagectomy
Lymph Node Excision
Female
business
Chemoradiotherapy
Abdominal surgery
Subjects
Details
- ISSN :
- 14322218
- Volume :
- 29
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Surgical endoscopy
- Accession number :
- edsair.doi.dedup.....3a1a1560dc41d07ed54b6da62d14c8e5