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Survival of a case of Bacillus cereus meningitis with brain abscess presenting as immune reconstitution syndrome after febrile neutropenia - a case report and literature review
- Source :
- BMC Infectious Diseases, BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-6 (2020)
- Publication Year :
- 2019
-
Abstract
- Background Bacillus cereus sometimes causes central nervous system infection, especially in compromised hosts. In cases of meningitis arising during neutropenia, CSF abnormalities tend to be subtle and can be easily overlooked, and mortality rate is high. We report a survived case of B. cereus meningitis/brain abscess in severe neutropenia, presenting as immune reconstitution syndrome. Case presentation A 54-year-old Japanese female with acute myelogenous leukemia developed B. cereus bacteremia and meningitis during consolidation chemotherapy. At the onset, she presented with mild meningism. She had marked leukocytopenia (WBC Conclusions With early diagnosis and prompt initiation and of antibiotics, the case was successfully treated without any sequelae. It is important to remember that, even under optimal antimicrobial therapy, bone marrow recovery can cause transient reaggravation of the disease. In such cases, timely and appropriate evaluation should be done to make the clinical decision to change, continue, or intensify treatment.
- Subjects :
- Pediatrics
medicine.medical_specialty
Febrile neutropenia
Brain Abscess
Bacteremia
Case Report
Neutropenia
lcsh:Infectious and parasitic diseases
Meningitis, Bacterial
Leukocytopenia
Bacillus cereus
Immune Reconstitution Inflammatory Syndrome
Antimicrobial chemotherapy
Antineoplastic Combined Chemotherapy Protocols
Immune reconstitution syndrome
medicine
Humans
lcsh:RC109-216
Meningitis
Chemotherapy-Induced Febrile Neutropenia
Brain abscess
medicine.diagnostic_test
Lumbar puncture
business.industry
Meningism
Middle Aged
medicine.disease
Anti-Bacterial Agents
Leukemia, Myeloid, Acute
Infectious Diseases
Treatment Outcome
Female
medicine.symptom
business
Subjects
Details
- ISSN :
- 14712334
- Volume :
- 20
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC infectious diseases
- Accession number :
- edsair.doi.dedup.....3a08ce39a08c81888e6bd569ee51a75a