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Rise of multiple insecticide resistance in Anopheles funestus in Malawi: a major concern for malaria vector control
- Source :
- Malaria Journal
- Publication Year :
- 2015
- Publisher :
- Springer Science and Business Media LLC, 2015.
-
Abstract
- Background Deciphering the dynamics and evolution of insecticide resistance in malaria vectors is crucial for successful vector control. This study reports an increase of resistance intensity and a rise of multiple insecticide resistance in Anopheles funestus in Malawi leading to reduced bed net efficacy. Methods Anopheles funestus group mosquitoes were collected in southern Malawi and the species composition, Plasmodium infection rate, susceptibility to insecticides and molecular bases of the resistance were analysed. Results Mosquito collection revealed a predominance of An. funestus group mosquitoes with a high hybrid rate (12.2 %) suggesting extensive species hybridization. An. funestus sensu stricto was the main Plasmodium vector (4.8 % infection). Consistently high levels of resistance to pyrethroid and carbamate insecticides were recorded and had increased between 2009 and 2014. Furthermore, the 2014 collection exhibited multiple insecticide resistance, notably to DDT, contrary to 2009. Increased pyrethroid resistance correlates with reduced efficacy of bed nets (
- Subjects :
- Male
Malawi
Insecticides
Veterinary medicine
Insecticide resistance
Mosquito Control
030231 tropical medicine
wc_765
Anopheles funestus
03 medical and health sciences
chemistry.chemical_compound
Dieldrin
0302 clinical medicine
Anopheles
qx_600
parasitic diseases
medicine
Animals
030304 developmental biology
0303 health sciences
Pyrethroid
Resistance (ecology)
biology
Research
Resistance mutation
medicine.disease
biology.organism_classification
Virology
Vector control
Malaria
Insect Vectors
3. Good health
Mosquito control
Infectious Diseases
qx_650
chemistry
Vector (epidemiology)
Mutation
Female
Parasitology
qx_515
Subjects
Details
- ISSN :
- 14752875
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Malaria Journal
- Accession number :
- edsair.doi.dedup.....39dfef63bfa3d941db6c7b2dd675b8c9