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Participation, retention and uptake in a multicentre pre-exposure prophylaxis cohort using online, smartphone-compatible data collection
- Source :
- HIV medicine, vol. 23, no. 2, pp. 146-158, Hovaguimian, F; Martin, E; Reinacher, M; Rasi, M; Schmidt, A J; Bernasconi, E; El Amari, E B; Braun, D L; Calmy, A; Darling, K; Christinet, V; Depmeier, C; Hauser, C; Läuchli, S; Notter, J; Stoeckle, M; Surial, B; Vernazza, P; Bruggmann, P; Tarr, P; ... (2022). Participation, retention and uptake in a multicentre pre-exposure prophylaxis cohort using online, smartphone-compatible data collection. HIV medicine, 23(2), pp. 146-158. Wiley 10.1111/hiv.13175
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- OBJECTIVES The aim of the study was to assess the feasibility of a national pre-exposure prophylaxis (PrEP) programme using smartphone-compatible data collection. METHODS This was a multicentre cohort study (NCT03893188) enrolling individuals interested in PrEP in Switzerland. All centres participate in the SwissPrEPared programme, which uses smartphone-compatible data collection. Feasibility was assessed after centres had enrolled at least one participant. Participants were HIV-negative individuals presenting for PrEP counselling. Outcomes were participation (number enrolled/number eligible), enrolment rates (number enrolled per month), retention at first follow-up (number with first follow-up/number enrolled), and uptake (proportion attending first visit as scheduled). Participant characteristics were compared between those retained after baseline assessment and those who dropped out. RESULTS Between April 2019 and January 2020, 987 individuals were assessed for eligibility, of whom 969 were enrolled (participation: 98.2%). The median enrolment rate was 86 per month [interquartile range (IQR) 52-137]. Retention at first follow-up and uptake were both 80.7% (782/969 and 532/659, respectively). At enrolment, the median age was 40 (IQR 33-47) years, 95% were men who have sex with men, 47% had a university degree, and 75.5% were already taking PrEP. Most reported multiple casual partners (89.2%), previous sexually transmitted infections (74%) and sexualized drug use (73.1%). At baseline, 25.5% tested positive for either syphilis, gonorrhoea or chlamydia. Participants who dropped out were at lower risk of HIV infection than those retained after baseline assessment. CONCLUSIONS In a national PrEP programme using smartphone-compatible data collection, participation, retention and uptake were high. Participants retained after baseline assessment were at high risk of HIV infection. Younger, less educated individuals were underrepresented in the SwissPrEPared cohort.
- Subjects :
- Adult
Male
10028 Institute of Medical Virology
medicine.medical_specialty
Anti-HIV Agents
HIV Infections
610 Medicine & health
Lower risk
Men who have sex with men
Cohort Studies
10234 Clinic for Infectious Diseases
Sexual and Gender Minorities
Pre-exposure prophylaxis
360 Social problems & social services
Interquartile range
Internal medicine
medicine
Humans
2736 Pharmacology (medical)
Pharmacology (medical)
Homosexuality, Male
Chlamydia
business.industry
Data Collection
Health Policy
Anti-HIV Agents/therapeutic use
HIV Infections/drug therapy
HIV Infections/epidemiology
HIV Infections/prevention & control
Pre-Exposure Prophylaxis
Smartphone
HIV
cohort study
pre-exposure prophylaxis
prevention programme
10060 Epidemiology, Biostatistics and Prevention Institute (EBPI)
2725 Infectious Diseases
medicine.disease
2719 Health Policy
Infectious Diseases
Cohort
Syphilis
business
Cohort study
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- HIV medicine, vol. 23, no. 2, pp. 146-158, Hovaguimian, F; Martin, E; Reinacher, M; Rasi, M; Schmidt, A J; Bernasconi, E; El Amari, E B; Braun, D L; Calmy, A; Darling, K; Christinet, V; Depmeier, C; Hauser, C; Läuchli, S; Notter, J; Stoeckle, M; Surial, B; Vernazza, P; Bruggmann, P; Tarr, P; ... (2022). Participation, retention and uptake in a multicentre pre-exposure prophylaxis cohort using online, smartphone-compatible data collection. HIV medicine, 23(2), pp. 146-158. Wiley 10.1111/hiv.13175 <http://dx.doi.org/10.1111/hiv.13175>
- Accession number :
- edsair.doi.dedup.....39d13ae7c59ae5dfbdb8247381999987
- Full Text :
- https://doi.org/10.48350/159992