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Xanthones Content in Swertia multicaulis D. Don from Nepal
- Source :
- Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry, Molecules, Vol 23, Iss 5, p 1067 (2018), Molecules; Volume 23; Issue 5; Pages: 1067
- Publication Year :
- 2018
- Publisher :
- MDPI AG, 2018.
-
Abstract
- The medicinal plant Swertia multicaulis D. Don was collected in Rasuwa District (Nepal) and the xanthone content of its ethyl acetate extracts was studied. The total amount of xanthones in S. multicaulis determined by HPLC reaches almost 13 g of xanthones per 1 kg of dry matter. The identification of xanthones in S. multicaulis was achieved by a combination of HPLC, LC–MS and LC–NMR. The final assignment of the individual chemical structures was provided by NMR, supported by preparative HPLC. In eight chromatographic peaks, four major xanthones were identified—1,3-dihydroxy-5,8-dimethoxyxanthone, 1-hydroxy-3,5,8-trimethoxyxanthone, bellidifolin (1,5,8-tri-hydroxy-3-methoxyxanthone), and decussatin (1-hydroxy-3,7,8-trimethoxyxanthone).
- Subjects :
- Gentianaceae
Magnetic Resonance Spectroscopy
Phytochemistry
Xanthones
Phytochemicals
Ethyl acetate
Secondary Metabolism
Pharmaceutical Science
LC–MS
01 natural sciences
Swertia
High-performance liquid chromatography
Article
Analytical Chemistry
lcsh:QD241-441
chemistry.chemical_compound
lcsh:Organic chemistry
Tandem Mass Spectrometry
Liquid chromatography–mass spectrometry
Drug Discovery
Xanthone
Swertia multicaulis
Physical and Theoretical Chemistry
Chromatography
Molecular Structure
biology
secondary metabolites
Plant Extracts
010405 organic chemistry
Organic Chemistry
HPLC
NMR
phytochemistry
biology.organism_classification
0104 chemical sciences
010404 medicinal & biomolecular chemistry
chemistry
Chemistry (miscellaneous)
Molecular Medicine
Chromatography, Liquid
Subjects
Details
- ISSN :
- 14203049
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....39772c0f07c15e3f1526823a4fb08cfb