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Impact of and Interaction between the Availability of Prior Examinations and DBT on the Interpretation of Negative and Benign Mammograms
- Source :
- Academic Radiology. 21:445-449
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- RATIONALE AND OBJECTIVES To assess the interaction between the availability of prior examinations and digital breast tomosynthesis (DBT) in decisions to recall a woman during interpretation of mammograms. MATERIALS AND METHODS Eight radiologists independently interpreted twice 36 mammography examinations, each of which had current and prior full-field digital mammography images (FFDM) and DBT under a Health Insurance Portability and Accountability Act-compliant, institutional review board-approved protocol (written consent waived). During the first reading, three sequential ratings were provided using FFDM only, followed by FFDM + DBT, and then followed by FFDM + DBT + priors. The second reading included FFDM only, then FFDM + priors, and then FFDM + priors + DBT. Twenty-two benign cases clinically recalled, 12 negative/benign examinations (not recalled), and two verified cancer cases were included. Recall recommendations and interaction between the effect of priors and DBT on decisions were assessed (P = .05 significance level) using generalized linear model (PROC GLIMMIX, SAS, version 9.3; SAS Institute, Cary, NC) accounting for case and reader variability. RESULTS Average recall rates in noncancer cases were significantly reduced (51%; P < .001) with the addition of DBT and with addition of priors (23%; P = .01). In absolute terms, the addition of DBT to FFDM reduced the recall rates from 0.67 to 0.42 and from 0.54 to 0.27 when DBT was available before and after priors, respectively. Recall reductions were from 0.64 to 0.54 and from 0.42 to 0.33 when priors were available before and after DBT, respectively. Regardless of the sequence in presentation, there were no statistically significant interactions between the effect of availability of DBT and priors (P = .80). CONCLUSIONS Availability of both priors and DBT are independent primary factors in reducing recall recommendations during mammographic interpretations.
- Subjects :
- Adult
medicine.medical_specialty
Digital mammography
Breast Neoplasms
Sensitivity and Specificity
Article
Statistical significance
medicine
Health insurance
Humans
Mammography
Radiology, Nuclear Medicine and imaging
Medical physics
Diagnostic Errors
False Negative Reactions
Aged
Observer Variation
medicine.diagnostic_test
Recall
business.industry
Reproducibility of Results
Digital Breast Tomosynthesis
Middle Aged
Combined Modality Therapy
Tomosynthesis
Radiographic Image Enhancement
Female
Tomography, X-Ray Computed
business
Nuclear medicine
Subjects
Details
- ISSN :
- 10766332
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Academic Radiology
- Accession number :
- edsair.doi.dedup.....3961cab44b820cf02cf9f528dee32438