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The Spread of Influenza A(H1N1)pdm09 Virus in Madagascar Described by a Sentinel Surveillance Network

Authors :
Soatiana Rajatonirina
Norosoa Harline Razanajatovo
Arnaud Orelle
Fanjasoa Rakotomanana
Yolande Raoelina Rajaona
Vincent Richard
Laurence Randrianasolo
Jean-Michel Heraud
Armand Eugène Randrianarivo-Solofoniaina
Institut Pasteur de Madagascar
Réseau International des Instituts Pasteur (RIIP)
Malagasy Ministry of Health
This work was feasible thanks to set-up of sentinel network supported by World Health Organization (WHO) Geneva (APW/Ref. OD/AP-08-02451), Sanofi-Pasteur, the French Ministry of Health, the United States Centers for Disease Control and Prevention (Cooperative Agreement Number: U51/IP000327-01), the United States Department of Health and Human Services (Grant Number 6 IDSEP060001-01-01) via the International Network of Pasteur Institutes, and the President Malaria Initiative program (USAIDS). The authors are therefore grateful to Wenqing Zhang from WHO Geneva, Be' atrice Barret and Myriam Beigeaud from Sanofi Pasteur, and Kathleen Victoir and Marc Jouan from the International Network of Pasteur Institutes. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Source :
PLoS ONE, PLoS ONE, Vol 7, Iss 5, p e37067 (2012), PLoS ONE, Public Library of Science, 2012, 7 (5), pp.e37067. ⟨10.1371/journal.pone.0037067⟩
Publication Year :
2012
Publisher :
Public Library of Science, 2012.

Abstract

International audience; The influenza A(H1N1)pdm09 virus has been a challenge for public health surveillance systems in all countries. In Antananarivo, the first imported case was reported on August 12, 2009. This work describes the spread of A(H1N1)pdm09 in Madagascar. METHODS: The diffusion of influenza A(H1N1)pdm09 in Madagascar was explored using notification data from a sentinel network. Clinical data were charted to identify peaks at each sentinel site and virological data was used to confirm viral circulation. RESULTS: From August 1, 2009 to February 28, 2010, 7,427 patients with influenza-like illness were reported. Most patients were aged 7 to 14 years. Laboratory tests confirmed infection with A(H1N1)pdm09 in 237 (33.2%) of 750 specimens. The incidence of patients differed between regions. By determining the epidemic peaks we traced the diffusion of the epidemic through locations and time in Madagascar. The first peak was detected during the epidemiological week 47-2009 in Antananarivo and the last one occurred in week 07-2010 in Tsiroanomandidy. CONCLUSION: Sentinel surveillance data can be used for describing epidemic trends, facilitating the development of interventions at the local level to mitigate disease spread and impact.

Details

Language :
English
ISSN :
19326203
Volume :
7
Issue :
5
Database :
OpenAIRE
Journal :
PLoS ONE
Accession number :
edsair.doi.dedup.....39612fbe095066d1c31e321cf9435a54
Full Text :
https://doi.org/10.1371/journal.pone.0037067⟩