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Early Evaluation of Organ Failure Using MELD-XI in Critically Ill Elderly COVID-19 Patients
- Source :
- Clinical Hemorheology and Microcirculation, Clinical Hemorheology and Microcirculation, 2021, 79 (1), pp.109--120. ⟨10.3233/CH-219202⟩, Bruno, R R, Wernly, B, Hornemann, J, Flaatten, H, Fjølner, J, Artigas, A, Bollen Pinto, B, Schefold, J C, Wolff, G, Baldia, P H, Binneboessel, S, Kelm, M, Beil, M, Sviri, S, van Heerden, P V, Szczeklik, W, Elhadi, M, Joannidis, M, Oeyen, S, Kondili, E, Wollborn, J, Marsh, B, Andersen, F H, Moreno, R, Leaver, S, Boumendil, A, De Lange, D W, Guidet, B, Jung, C & COVIP study group 2021, ' Early evaluation of organ failure using MELD-XI in critically ill elderly COVID-19 patients ', Clinical Hemorheology and Microcirculation, vol. 79, no. 1, pp. 109-120 . https://doi.org/10.3233/CH-219202
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- International audience; PURPOSE Critically ill elderly patients who suffer from Sars-CoV-2 disease are at high risk for organ failure. The modified MELD-XI score has not been evaluated for outcome prediction in these most vulnerable patients. METHODS The Corona Virus disease (COVID19) in Very Elderly Intensive Care Patients study (COVIP, NCT04321265) prospectively recruited patients on intensive care units (ICU), who were = 70 years. Data were collected from March 2020 to February 2021. The MELD-XI score was calculated using the highest serum bilirubin and creatinine on ICU admission. Univariate and multivariable logistic regression analyses were performed to assess associations between the MELD-XI score and mortality. The primary outcome was 30-day-mortality, the secondary outcomes were ICU- and 3-month-mortality. RESULTS In total, data from 2,993 patients were analyzed. Most patients had a MELD-XI
- Subjects :
- medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Physiology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Critical Illness
[SDV]Life Sciences [q-bio]
Disease
Logistic regression
Severity of Illness Index
chemistry.chemical_compound
Physiology (medical)
Intensive care
Internal medicine
medicine
Humans
610 Medicine & health
Aged
Creatinine
business.industry
Critically ill
SARS-CoV-2
Confounding
COVID-19
Hematology
Prognosis
body regions
[SDV] Life Sciences [q-bio]
chemistry
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- Language :
- English
- ISSN :
- 13860291
- Database :
- OpenAIRE
- Journal :
- Clinical Hemorheology and Microcirculation, Clinical Hemorheology and Microcirculation, 2021, 79 (1), pp.109--120. ⟨10.3233/CH-219202⟩, Bruno, R R, Wernly, B, Hornemann, J, Flaatten, H, Fjølner, J, Artigas, A, Bollen Pinto, B, Schefold, J C, Wolff, G, Baldia, P H, Binneboessel, S, Kelm, M, Beil, M, Sviri, S, van Heerden, P V, Szczeklik, W, Elhadi, M, Joannidis, M, Oeyen, S, Kondili, E, Wollborn, J, Marsh, B, Andersen, F H, Moreno, R, Leaver, S, Boumendil, A, De Lange, D W, Guidet, B, Jung, C & COVIP study group 2021, ' Early evaluation of organ failure using MELD-XI in critically ill elderly COVID-19 patients ', Clinical Hemorheology and Microcirculation, vol. 79, no. 1, pp. 109-120 . https://doi.org/10.3233/CH-219202
- Accession number :
- edsair.doi.dedup.....390c2139cc05fd2a80227e2611c60dbb