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Situs anomalies on prenatal MRI
- Source :
- European Journal of Radiology. 81:e495-e501
- Publication Year :
- 2012
- Publisher :
- Elsevier BV, 2012.
-
Abstract
- Objective Situs anomalies refer to an abnormal organ arrangement, which may be associated with severe errors of development. Due regard being given to prenatal magnetic resonance imaging (MRI) as an adjunct to ultrasonography (US), this study sought to demonstrate the in utero visualization of situs anomalies on MRI, compared to US. Materials and methods This retrospective study included 12 fetuses with situs anomalies depicted on fetal MRI using prenatal US as a comparison modality. With an MRI standard protocol, the whole fetus was assessed for anomalies, with regard to the position and morphology of the following structures: heart; venous drainage and aorta; stomach and intestines; liver and gallbladder; and the presence and number of spleens. Results Situs inversus totalis was found in 3/12 fetuses; situs inversus with levocardia in 1/12 fetuses; situs inversus abdominis in 2/12 fetuses; situs ambiguous with polysplenia in 3/12 fetuses, and with asplenia in 2/12 fetuses; and isolated dextrocardia in 1/12 fetuses. Congenital heart defects (CHDs), vascular anomalies, and intestinal malrotations were the most frequent associated malformations. In 5/12 cases, the US and MRI diagnoses were concordant. Compared to US, in 7/12 cases, additional MRI findings specified the situs anomaly, but CHDs were only partially visualized in six cases. Conclusions Our initial MRI results demonstrate the visualization of situs anomalies and associated malformations in utero , which may provide important information for perinatal management. Using a standard protocol, MRI may identify additional findings, compared to US, which confirm and specify the situs anomaly, but, with limited MRI visualization of fetal CHDs.
- Subjects :
- Male
congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
Asplenia
Prenatal diagnosis
Heterotaxy Syndrome
Sensitivity and Specificity
Situs
Prenatal Diagnosis
otorhinolaryngologic diseases
medicine
Humans
Radiology, Nuclear Medicine and imaging
Ultrasonography
medicine.diagnostic_test
business.industry
Gallbladder
Reproducibility of Results
Magnetic resonance imaging
General Medicine
medicine.disease
Magnetic Resonance Imaging
Situs inversus
medicine.anatomical_structure
Levocardia
Female
Polysplenia
Radiology
business
Subjects
Details
- ISSN :
- 0720048X
- Volume :
- 81
- Database :
- OpenAIRE
- Journal :
- European Journal of Radiology
- Accession number :
- edsair.doi.dedup.....3902b1e47e7f1508916a79e5c41d4465