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Fulminant cryptococcal meningoencephalitis after successful treatment of primary cutaneous cryptococcosis
- Source :
- Germs
- Publication Year :
- 2020
- Publisher :
- Asociatia Pentru Cresterea Vizibilitatii Cercetarii Stiintifice (ACVCS), 2020.
-
Abstract
- Introduction Cryptococcal meningoencephalitis is a life-threatening disease affecting mainly immunocompromised hosts. Case report We present a case of a 64-year-old immunocompetent patient, who initially developed a traumatic scalp skin infection due to Cryptococcus neoformans. The patient received oral fluconazole and subsequently liposomal amphotericin B due to the development of resistance with resolution of the infection. Two years later, during chemotherapy for newly diagnosed gastric and lung cancer, he developed fulminant cryptococcal meningoencephalitis, which did not respond to liposomal amphotericin B and flucytosine. Conclusions To our knowledge, this is the first case of fulminant cryptococcal meningoencephalitis following long latency after adequately treated primary cutaneous infection.
- Subjects :
- Microbiology (medical)
Cryptococcus neoformans
Chemotherapy
medicine.medical_specialty
General Immunology and Microbiology
biology
Epidemiology
business.industry
Fulminant
medicine.medical_treatment
Public Health, Environmental and Occupational Health
Cryptococcus
Case Report
Skin infection
biology.organism_classification
medicine.disease
Dermatology
Flucytosine
Infectious Diseases
Medicine
business
Meningitis
Fluconazole
medicine.drug
Subjects
Details
- ISSN :
- 22482997
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- GERMS
- Accession number :
- edsair.doi.dedup.....38f1e6c153981ffeb744508a281656ad