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Loss of a Callose Synthase Results in Salicylic Acid-Dependent Disease Resistance
- Source :
- Science. 301:969-972
- Publication Year :
- 2003
- Publisher :
- American Association for the Advancement of Science (AAAS), 2003.
-
Abstract
- Plants attacked by pathogens rapidly deposit callose, a β-1,3-glucan, at wound sites. Traditionally, this deposition is thought to reinforce the cell wall and is regarded as a defense response. Surprisingly, here we found that powdery mildew resistant 4 ( pmr4 ), a mutant lacking pathogen-induced callose, became resistant to pathogens, rather than more susceptible. This resistance was due to mutation of a callose synthase, resulting in a loss of the induced callose response. Double-mutant analysis indicated that blocking the salicylic acid (SA) defense signaling pathway was sufficient to restore susceptibility to pmr4 mutants. Thus, callose or callose synthase negatively regulates the SA pathway.
- Subjects :
- Erysiphe cichoracearum
Mutant
Arabidopsis
Plant disease resistance
Genes, Plant
Microbiology
chemistry.chemical_compound
Ascomycota
Gene Expression Regulation, Plant
Arabidopsis thaliana
Extrahaustorial membrane
Glucans
Alleles
Oligonucleotide Array Sequence Analysis
Plant Diseases
Multidisciplinary
Cell Death
biology
Gene Expression Profiling
Callose
Membrane Proteins
biology.organism_classification
Plant Leaves
Phenotype
chemistry
Glucosyltransferases
Mutation
Schizosaccharomyces pombe Proteins
Salicylic Acid
Powdery mildew
Salicylic acid
Signal Transduction
Subjects
Details
- ISSN :
- 10959203 and 00368075
- Volume :
- 301
- Database :
- OpenAIRE
- Journal :
- Science
- Accession number :
- edsair.doi.dedup.....38cf4aec1c111ac2ae276d39cd7a23e0