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Primary spinal epidural manifestation of malignant lymphoma
- Source :
- Histopathology. 29(3)
- Publication Year :
- 1996
-
Abstract
- The clinical, histological and immunomorphological data in 19 cases of primary spinal epidural manifestation of malignant lymphomas collected between 1974 and 1994 are reported. The age of the patients varied between 11 and 87 years with a mean age of 56.3 years. There was a slight male predominance (11:8). In most cases, the onset of the clinical symptoms was rapid. The preferential tumour localization was the epidural space related to the thoracal vertebral bone. In each case, decompressive laminectomy was performed. The tumours were histologically and immunomorphologically classified as B-cell lymphomas (14 of 19), T-cell lymphomas (3 of 19) and anaplastic plasmacytoma (1 of 19). Except for one case, post-operative staging did not reveal anything other than epidural manifestation of the malignant lymphoma. The vertebral bone, however, was involved in seven cases. Irradiation alone, or in combination with chemotherapy, was performed as additional therapy. The post-operative survival time was variable.
- Subjects :
- Adult
Male
Pathology
medicine.medical_specialty
Histology
Adolescent
Lymphoma
medicine.medical_treatment
Pathology and Forensic Medicine
Malignant lymphoma
Medicine
Humans
Anaplastic Plasmacytoma
Child
Aged
Retrospective Studies
Aged, 80 and over
Chemotherapy
business.industry
Antibodies, Monoclonal
Retrospective cohort study
General Medicine
Middle Aged
Spinal cord
Immunohistochemistry
Epidural space
Spinal epidural
medicine.anatomical_structure
Female
Epidural Neoplasms
business
Subjects
Details
- ISSN :
- 03090167
- Volume :
- 29
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Histopathology
- Accession number :
- edsair.doi.dedup.....38c603f078f7f1afc3c8d7c49fdf33e7