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Quantitative Assessment of Retinal Capillary Vessel Density and Foveal Avascular Zone Area in Central Serous Chorioretinopathy Using OCTA
- Source :
- Ophthalmologica. 243:370-378
- Publication Year :
- 2020
- Publisher :
- S. Karger AG, 2020.
-
Abstract
- Purpose: To quantitatively assess the retinal capillary vessel density (VD) and foveal avascular zone (FAZ) area in acute and chronic central serous chorioretinopathy (CSC) patients compared to healthy subjects using optical coherence tomography angiography (OCTA) and determine their correlation with visual acuity (VA). Methods: This was a cross-sectional, case-control study. All subjects were divided into three groups: acute CSC, chronic CSC, and healthy controls. The best-corrected VA test, optical coherence tomography, and OCTA were performed on the same day. In this study, we recorded and compared the main data of FAZ and VD in 3 × 3 mm OCTA images among three groups, also calculated the correlation between OCTA variables and VA in CSC patients. Results: A total of 148 subjects (148 eyes) were included in this study, with 50 eyes in acute CSC, 48 eyes in chronic CSC, and 50 eyes in control groups. The mean age was 50.11 ± 8.14 years. Chronic CSC had the significantly lowest VD both on the superficial and deep retina and the largest FAZ (0.39 ± 0.13 mm2) compared to acute CSC and controls (all p < 0.05). There was no statistical difference between acute CSC and controls on VD or FAZ (both p > 0.05). In chronic CSC, both the decreased VD on deep retina and expanded FAZ were correlated with a worse VA (both p < 0.05). Conclusions: OCTA could serve as a reliable tool to evaluate different courses of CSC quantitively. In 3 × 3 mm OCTA images, both decreased VD and expanded FAZ were observed in chronic CSC patients.
- Subjects :
- Male
medicine.medical_specialty
Visual acuity
genetic structures
Fundus Oculi
01 natural sciences
03 medical and health sciences
0302 clinical medicine
Vessel density
Optical coherence tomography
Ophthalmology
Retinal capillary
medicine
Humans
Macula Lutea
Fluorescein Angiography
0101 mathematics
Retrospective Studies
Retina
medicine.diagnostic_test
business.industry
010102 general mathematics
Retinal Vessels
General Medicine
Optical coherence tomography angiography
Foveal avascular zone
Middle Aged
eye diseases
Sensory Systems
Capillaries
Serous fluid
Cross-Sectional Studies
medicine.anatomical_structure
Central Serous Chorioretinopathy
030221 ophthalmology & optometry
Female
sense organs
medicine.symptom
business
Tomography, Optical Coherence
Subjects
Details
- ISSN :
- 14230267 and 00303755
- Volume :
- 243
- Database :
- OpenAIRE
- Journal :
- Ophthalmologica
- Accession number :
- edsair.doi.dedup.....38c2378281ba6ddc8687c86b97d23e21