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Chemical analysis of Karenia papilionacea
- Source :
- Toxicon : official journal of the International Society on Toxinology. 101
- Publication Year :
- 2015
-
Abstract
- One of the most widely studied organisms responsible for Harmful Algal Blooms (HABs) is the marine dinoflagellate Karenia brevis. This organism produces neurotoxic compounds known as brevetoxins. A related dinoflagellate, Karenia papilionacea, has been reported to occasionally co-bloom with K. brevis but has received little attention as a possible toxin producing species. Therefore, our aim was to investigate the toxin profile for K. papilionacea. A toxic fraction was identified using a cell based cytotoxicity assay and the toxin was isolated and identified as the ladder frame polyether brevetoxin-2 (PbTx-2) using mass spectrometry (MS) and nuclear magnetic resonance (NMR). Toxin production in K. papilionacea increased in response to hypoosmotic stress, as previously observed in K. brevis.
- Subjects :
- Karenia papilionacea
Magnetic Resonance Spectroscopy
biology
Toxin
Harmful Algal Bloom
Oxocins
Dinoflagellate
Toxicology
biology.organism_classification
medicine.disease_cause
Algal bloom
Microbiology
Brevetoxin
Osmotic Pressure
Stress, Physiological
medicine
Dinoflagellida
Marine Toxins
Karenia brevis
Cytotoxicity
Cell based
Subjects
Details
- ISSN :
- 18793150
- Volume :
- 101
- Database :
- OpenAIRE
- Journal :
- Toxicon : official journal of the International Society on Toxinology
- Accession number :
- edsair.doi.dedup.....38b8055ce6ebe60f842d8ea8ad6421ec