Back to Search
Start Over
Mobile community-based active case-finding for tuberculosis among older populations in rural Cambodia
Mobile community-based active case-finding for tuberculosis among older populations in rural Cambodia
- Source :
- International Journal of Tuberculosis and Lung Disease, International Journal of Tuberculosis and Lung Disease, International Union Against Tuberculosis and Lung Disease, 2019, 23 (10), pp.1107-1114. ⟨10.5588/ijtld.18.0611⟩
- Publication Year :
- 2019
- Publisher :
- International Union Against Tuberculosis and Lung Disease, 2019.
-
Abstract
- OBJECTIVE: To systematically screen older rural populations in Cambodia for tuberculosis (TB) and develop an effective active case-finding (ACF) model for this TB high-risk group.DESIGN: A retrospective study using routinely collected programmatic data on community-based ACF among people aged ≥55 years using TB symptoms and systematic chest radiography (CXR) screening, followed by Xpert® MTB/RIF testing for participants with positive screening results and TB culture for certain Xpert-negative specimens.RESULTS: Of 22 101 participants included in the analysis, 7469 (33.8%) were screening-positive and 5960 (27.0%) underwent Xpert testing. Pulmonary TB was identified in 482 (2.2%) individuals: 288 (1.3%) were bacteriologically confirmed (253 using Xpert, 35 using culture) and 194 (0.9%) were clinically diagnosed. Eighty-seven people needed to be screened in order to diagnose one Xpert-positive case. Among the Xpert-positive cases, only 31.6% (80/253) reported cough ≥2 weeks, and 39.9% (101/253) were asymptomatic but had a CXR suggestive of active TB. Treatment uptake was 97.3% (469/482), and treatment success was 88.0% (424/482).CONCLUSIONS: Community-based ACF was effective in detecting and successfully treating older TB patients, most of whom might otherwise have remained undiagnosed. Mobile CXR appears to be crucial in identifying a high number of asymptomatic, bacteriologically confirmed cases.
- Subjects :
- Male
Rural Population
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Tuberculosis
diagnosis
030231 tropical medicine
Antitubercular Agents
detection
elderly
Asymptomatic
Older population
03 medical and health sciences
0302 clinical medicine
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Active tb
Internal medicine
medicine
Humans
Mass Screening
030212 general & internal medicine
Tuberculosis, Pulmonary
Aged
Retrospective Studies
business.industry
screening
Retrospective cohort study
Middle Aged
Patient Acceptance of Health Care
medicine.disease
chest X-ray
3. Good health
Infectious Diseases
Treatment success
Cough
Case finding
Female
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
medicine.symptom
Cambodia
business
Rural population
Subjects
Details
- ISSN :
- 10273719 and 18157920
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- The International Journal of Tuberculosis and Lung Disease
- Accession number :
- edsair.doi.dedup.....3886c2f341a80d0f9c0b90295590b400
- Full Text :
- https://doi.org/10.5588/ijtld.18.0611