Supplementary Data from Autocrine IL6-Mediated Activation of the STAT3–DNMT Axis Silences the TNFα–RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells

Supplemental Figures 1-7. Figure S1. IRF8 expression profiles in subsets of immune cells in spleens of tumor-bearing mice. Figure S2. IRF8 expression profiles in subsets of immune cells in peripheral blood of tumor-bearing mice. Figure S3. DNA methylation and MDSC accumulation in tumor-bearing mice. Figure S4. Inhibition of DNA methylation activates antigen-specific CTLs in tumor-bearing mice. Figure S5. Neutralization of TNFα increases tumor growth and MDSC accumulation. Figure S6. RIP1 and RIP3 are expressed in MDSCs. Figure S7. IL6 expression level in human colon carcinoma and melanoma. Table S1. Colorectal cancer patient data. Table S2. Colon cancer patient data.