Frequency of bone abnormalities and associated factors in a Spanish cohort of HIV-infected patients

Methods This is a cross-sectional study to evaluate the bone mineral density (BMD) in HIV-infected patients from a HIV unit of a Spanish university hospital. All patients with at least one evaluation of BMD of total body, lumbar spine and femoral neck measured by dual-energy X-ray absorptiometry (DEXA) were included in the analysis. The MannWhitney U test was used to compare two populations (normal and abnormal bone mineralization), and the Kruskal Wallis test to compare normal, osteopenia and osteoporosis populations (based on the World Health Organization criteria). A uniand multivariant logistic regression were used to analyse the association between HIV disease status, demographics and antiretroviral treatments with the frequency of bone abnormalities.