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Multiresidue determination of organochlorines in fish oil by GC–MS: A new strategy in the sample preparation
- Source :
- Talanta. 81:887-893
- Publication Year :
- 2010
- Publisher :
- Elsevier BV, 2010.
-
Abstract
- A rapid, economic and environmentally friendly analytical methodology has been implemented for the determination of alpha-, beta-, gamma- and delta-HCH, p,p'-DDT, p,p'-DDD and p,p'-DDE, PCBs congeners #28, #52, #101, #153, #138 and #180 and Hexachlorobenzene in fish oil. 1,2,3,4-Tetrachloronaphtalene was used as internal standard. The sample preparation, consisting of a single step of clean-up and fractionation, took place in a column filled with different layers of neutral and sulphuric acid modified silica. The analytes were eluted by vacuum with of hexane. Significant reduction in terms of solvents, sorbents, and analysis time was achieved in comparison with literature. Gas chromatography coupled to mass spectrometry was used for the separation and determination of the analytes. The instrumental limits of detection were from 0.1 to 1.3ngmL(-1) and the response of the detector was linear up to 200ngmL(-1). The separation proved to be precise (RSD
- Subjects :
- Detection limit
Time Factors
Chromatography
Chemistry
Elution
Pesticide Residues
Reproducibility of Results
Food Contamination
Fractionation
Chemistry Techniques, Analytical
Gas Chromatography-Mass Spectrometry
Analytical Chemistry
Electron capture detector
Fish Oils
Certified reference materials
Limit of Detection
Calibration
Dietary Supplements
Fatty Acids, Omega-3
Hydrocarbons, Chlorinated
Sample preparation
Gas chromatography
Gas chromatography–mass spectrometry
Food Analysis
Subjects
Details
- ISSN :
- 00399140
- Volume :
- 81
- Database :
- OpenAIRE
- Journal :
- Talanta
- Accession number :
- edsair.doi.dedup.....384b2733f84d15906b6a314381fbc4ad