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Enamel matrix protein derivative and/or synthetic bone substitute for the treatment of mandibular class II buccal furcation defects. A 12-month randomized clinical trial
- Source :
- Clinical oral investigations. 20(7)
- Publication Year :
- 2015
-
Abstract
- This study aims to clinically evaluate the treatment of mandibular class II furcation defects with enamel matrix derivative (EMD) and/or a bone substitute graft made of β-tricalcium phosphate/hydroxyapatite (βTCP/HA). Forty-one patients, presenting a mandibular class II buccal furcation defect, probing pocket depth (PPD) ≥4 mm and bleeding on probing, were included. They were randomly assigned to the groups: 1—EMD (n = 13); 2—βTCP/HA (n = 14); 3—EMD + βTCP/HA (n = 14). Plaque index (PI), gingival index (GI), relative gingival margin position (RGMP), relative vertical and horizontal attachment level (RVCAL and RHCAL), and PPD were evaluated at baseline and 6 and 12 months. The mean horizontal clinical attachment level gain was considered the primary outcome variable. No significant intragroup differences were observed for RGMP, but significant changes were observed for RVCAL, RHCAL, and PPD for all groups (p
- Subjects :
- 0301 basic medicine
Male
Bleeding on probing
Dentistry
Mandible
Surgical Flaps
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
Dental Enamel Proteins
law
Enamel matrix derivative
Medicine
Humans
General Dentistry
Orthodontics
Enamel paint
business.industry
Furcation Defects
Dental Plaque Index
Furcation defect
030206 dentistry
Buccal administration
Middle Aged
030104 developmental biology
Treatment Outcome
visual_art
Bone Substitutes
visual_art.visual_art_medium
Female
Hydroxyapatites
medicine.symptom
Periodontal Index
business
Gingival margin
Subjects
Details
- ISSN :
- 14363771
- Volume :
- 20
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Clinical oral investigations
- Accession number :
- edsair.doi.dedup.....38463d60326ca07f226ac5a91de35ad1