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Can Admission Neutrophil to Lymphocyte Ratio Predict Infarct-Related Artery Patency in ST-Segment Elevation Myocardial Infarction

Authors :
Hamza Sunman
Mehmet Erat
Sadik Acikel
Murat Bilgin
Tolga Han Efe
Tolga Çimen
Ekrem Yeter
Ahmet Akyel
Mehmet Dogan
Source :
Clinical and Applied Thrombosis/Hemostasis. 21:172-176
Publication Year :
2013
Publisher :
SAGE Publications, 2013.

Abstract

Objectives: In this study, we aimed to investigate the relationship between neutrophil to lymphocyte ratio (NLR) and infarct-related artery (IRA) patency in patients with ST-segment elevation myocardial infarction (STEMI). Methods: A total of 349 patients with STEMI were recruited to this retrospective study. Baseline characteristics were reviewed. Patency of IRA was evaluated by thrombolysis in myocardial infarction flow grade. Results: Of all patients, 293 patients formed the occluded IRA group and 56 patients formed the patent IRA group. The NLR was significantly higher in occluded IRA group (4.4 ± 4.1 vs 1.9 ± 1.1, P < .001). Glucose levels were also higher in occluded IRA group (171.3 ± 78.0 vs 144.7 ± 49.7, P = .022). Regression analysis demonstrated admission NLR and plasma glucose levels as independent predictors of IRA patency. Conclusion: In this study, we found that admission NLR and glucose levels were higher in patients with occluded IRA than in patients with STEMI. We also found that NLR and glucose levels were independent predictors of IRA patency. Because hemogram is a cheap, fast, and widely available test, it can be used in daily practice as a predictor of IRA patency.

Details

ISSN :
19382723 and 10760296
Volume :
21
Database :
OpenAIRE
Journal :
Clinical and Applied Thrombosis/Hemostasis
Accession number :
edsair.doi.dedup.....38454adb99df122462056339246e407f
Full Text :
https://doi.org/10.1177/1076029613515071