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Inter-pregnancy interval and associated adverse maternal outcomes among women who delivered at Kilimanjaro Christian Medical Centre in Tanzania, 2000-2015
- Source :
- PLoS ONE, Vol 15, Iss 2, p e0228330 (2020), PLoS ONE
- Publication Year :
- 2020
- Publisher :
- Public Library of Science (PLoS), 2020.
-
Abstract
- Inter-pregnancy interval is an important determinant of both maternal and child health. Suboptimal inter-pregnancy interval has been associated with adverse maternal outcomes -including postpartum hemorrhage and hypertensive disorders, direct causes of maternal mortality. Both overall maternal mortality and the contribution of postpartum hemorrhage on maternal mortality have increased in Tanzania. If we are to achieve sustainable development goal (SDG) number 3.1 to reduce the global maternal mortality ration to less than 70 per 100,000 live births by 2030, it is highly important that such contributors are dealt with. This study aimed to determine the distribution and trends of inter-pregnancy interval and to deduce its association with adverse maternal outcomes among women who delivered at Kilimanjaro Christian Medical Centre (2000-2015).A retrospective cohort study was designed using Kilimanjaro Christian Medical Centre medical birth registry data for women who delivered from 2000 to 2015. Women with at least two births recorded in the registry were included. A total of 7,995 births from 6,612 mothers were analyzed. Anemia during pregnancy, post-partum hemorrhage and pre-eclampsia were adverse maternal outcomes of interest. Data analysis was performed using multivariable logistic regression models allowing for robust standard errors. Crude and adjusted odds ratio with their respective 95% confidence intervals were estimated. More than half (51.7%) of non-first births were born within sub-optimal IPI. The median IPI was 34 months (IQR: 33.5 months). The median IPI increased from 11 months in 2002 to 35 months in 2006 and plateaued until 2014, but it rose to 41.6 months in 2015. Median IPI was shorter in young women
- Subjects :
- Critical Care and Emergency Medicine
Maternal Health
Blood Pressure
Pathology and Laboratory Medicine
Vascular Medicine
Tanzania
Labor and Delivery
Pre-Eclampsia
Pregnancy
Medicine and Health Sciences
Odds Ratio
Registries
Young adult
Multidisciplinary
Obstetrics
Age Factors
Obstetrics and Gynecology
Anemia
Hematology
Severe Blood Loss
Birth order
Maternal Mortality
Family planning
Hypertension
Medicine
Female
Research Article
Adult
medicine.medical_specialty
Science
Hemorrhage
Lower risk
Young Adult
Signs and Symptoms
Birth Intervals
Diagnostic Medicine
Antenatal Care
Hypertensive Disorders in Pregnancy
medicine
Humans
Retrospective Studies
business.industry
Postpartum Hemorrhage
Retrospective cohort study
Odds ratio
medicine.disease
Preeclampsia
Confidence interval
Pregnancy Complications
Logistic Models
Birth
Women's Health
business
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 15
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....38406294206149dd25fd805db8acc0d1