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The relationship between T‐wave peak‐to‐end interval and hemodynamic parameters in patients with pulmonary arterial hypertension
- Source :
- Annals of Noninvasive Electrocardiology, Vol 25, Iss 5, Pp n/a-n/a (2020), Annals of Noninvasive Electrocardiology
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Background T‐wave peak‐to‐end interval (TPEI) is a measure of repolarization dispersion on surface electrocardiogram (ECG). TPEI has been reported as a prognostic parameter with heart disorders. In this study, we aimed to evaluate the relationship between echocardiogram‐derived right heart parameters, right heart catheterization (RHC) measurements, and TPEI in patients with precapillary pulmonary arterial hypertension (PAH). Methods Thirty‐eight patients (29 females and 9 males, mean age of 54.9 ± 10.9 years) who had undergone RHC for a preliminary diagnosis of pulmonary hypertension (PH) were included in the study. We performed transthoracic echocardiography (TTE), and resting 12‐lead ECG was recorded before RHC. TPEI was measured from leads of V1‐V6, DII, DIII, and aVF, and these values are averaged to obtain the global TPEI. Results Duration of TPEI was significantly correlated with mean PAP, pulmonary vascular resistance (PVR), and cardiac index (CI). Longer TPEI was associated with higher N terminal probrain natriuretic peptide (NT pro‐BNP) level, lower 6‐min walk distance (6MWD), and lower tricuspid annular plane systolic excursion (TAPSE). Conclusion Prolongation of TPEI could be a new predictor of adverse outcome in PAH and may provide additional prognostic information for patients with PAH.
- Subjects :
- Male
medicine.medical_specialty
T‐wave peak‐to‐end interval
medicine.drug_class
Cardiac index
Hemodynamics
Pulmonary Artery
030204 cardiovascular system & hematology
Electrocardiography
03 medical and health sciences
Heart disorder
0302 clinical medicine
Physiology (medical)
Internal medicine
pulmonary arterial hypertension
medicine
Natriuretic peptide
Humans
Repolarization
Diseases of the circulatory (Cardiovascular) system
In patient
right heart catheterization
030212 general & internal medicine
cardiovascular diseases
business.industry
ECG
Original Articles
General Medicine
Middle Aged
medicine.disease
Pulmonary hypertension
medicine.anatomical_structure
Echocardiography
RC666-701
Cardiology
Vascular resistance
Original Article
Female
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- Language :
- English
- Volume :
- 25
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Annals of Noninvasive Electrocardiology
- Accession number :
- edsair.doi.dedup.....3829ba79b380b3150e2d506a8764d919