Back to Search Start Over

Supplementary Figure S1 from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside

Authors :
George Coukos
Rosemarie Mick
Daniel J. Powell
Drew A. Torigian
Brian J. Czerniecki
Michael Kalos
Bruce L. Levine
Harvey L. Nisenbaum
Lori Smith
Gina M. Mantia-Smaldone
Kathleen Montone
Nikolaos Svoronos
Gregory T. Motz
Andrea R. Hagemann
Janos Tanyi
Lana E. Kandalaft
Cheryl Lai-Lai Chiang
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Figure S1 - PDF file 81K, DCs pulsed with HOCl-L efficiently tumor-specific CD4+ and SIINFEKL-specific CD8+ T-cell responses in mice. A, representative dotplots showing the % of SIINFEKL-pentamer specific CD8+ T-cells (gated) in the spleens of mice following DC-lysate vaccinations. B, the % of CD3+CD4+ IFN-gamma secreting T-cells in response to live ID8-ova tumor cells was quantified in spleens 2 weeks after the 3rd vaccine. Data was the mean of 3 independent experiments with 5 mice in each experiment

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....37ea8acebcca59bcda38021527c2455c
Full Text :
https://doi.org/10.1158/1078-0432.22447295